Abstract
Patients with delirium may fail to respond to standard therapies. Sixteen patients with management-refractory hyperactive delirium responded to adjunctive valproic acid, with complete resolution of hyperactive delirium in 13 cases. A rationale for using valproic acid in such circumstances is discussed.
MeSH terms
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Adult
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Aged
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Aged, 80 and over
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Antimanic Agents / therapeutic use*
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Antipsychotic Agents / therapeutic use*
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Benzodiazepines / therapeutic use*
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Delirium / drug therapy*
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Drug Therapy, Combination
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Female
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Humans
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Male
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Middle Aged
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Retrospective Studies
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Treatment Outcome
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Valproic Acid / therapeutic use*
Substances
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Antimanic Agents
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Antipsychotic Agents
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Benzodiazepines
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Valproic Acid